Ambient and Oral Product

Dosing and Administration of drugs: dose and duration of treatment depend on the form and dose of other drugs, taken together with tiohuaninom; absorption after oral administration of variable, the level of drug in plasma can decrease as a result of vomiting or eating; short course can be applied to any to an initial treatment prior to maintenance treatment, namely stadiyiyi induction, consolidation and intensification of treatment is not recommended to use scale economy maintenance therapy or similar long-term treatment in connection with a high risk of liver toxicity, the usual dose for adults is 60 -200 mh/m2/dobu for children - the same dosage as for adults, with calculation of dose according to body surface area. Preparations of drugs: 40 mg tabl.po number 25 in the vial scale economy . Pharmacotherapeutic group: L01VS03 - Antineoplastic agents. Indications for use drugs: h.leykoz (h.miyeloblastnyy h.limfoblastnyy leukemia and Tender Loving Care exacerbation hr.hranulotsytarnoho leukemia. 400 mg vial. Side effects and complications in the use of drugs: nausea, vomiting, stomach pain, dizziness, diarrhea, rare - gastrointestinal bleeding, ulcers of the stomach and duodenum, stomatitis, liver dysfunction and kidney, sometimes hour pancreatitis, inhibition of hematopoiesis, cardiac activities of hypersensitivity reactions; yayazhki side effects are rarely observed (possible severe leukopenia, thrombocytopenia, anemia, liver damage (hepatitis g), dehydration, Carrier inflammation of the intestine, symptoms leykoentsefality, interstetsiyna pneumonia anosmiya, rest angina) the degree of toxic effect depends on the method and the input mode, dizziness, nausea and vomiting decreased with the daily dose fractionation. Preparations of drugs: cap. Structural analogues of purine. scale economy 2-4 g / day; course at an oral dose - 30-40 g; can use smaller doses over a longer time (dose can be reduced in elderly patients and in the later stages of the disease) in the schemes and polychemotherapy as adjuvant in radiotherapy is used in doses equal to or less than the dose used in monotherapy, if necessary, treatment is repeated at intervals of 1,5-2 months. until breeding powder; required amount of diluted Mr Fasting Blood Sugar should be further diluted to 100 ml of 0,9% by Mr sodium chloride and introduced to and within 10 minutes, before each dose is recommended to check complete blood count and platelets (absolute number of neutrophils should be? 1.5 h109l, platelets? 100h109l) dose correction before the next cycle should be based on the smallest values of hematological indices or maximum nehematolohichniy toxicity of the last cycle of therapy to assess scale economy function and kidney should periodically conduct biochemical analysis blood treatment can be stopped in view of sufficient time for recovery; pemetreksed not recommended for use in pediatric practice because its efficacy and safety in this group of patients not identified. Dosing and Administration of drugs: when administered orally daily dose is 20-30 mg / kg (1,2-1,6 g or 3 cap.) But can reach 2 g (5 cap.) Dose divided by 2 methods and take daily every 12 hours.